Countdown to Future-Ready Execution
September 15-17, 2026

Execution at Scale in the Age of AI and Industrial Realignment

December 8–10, 2026
Sheraton hotel, San Francisco, California

A cross-industry enterprise forum for leaders navigating AI acceleration, manufacturing reinvention, enterprise modernization, supply chain redesign, and strategic execution pressure.

Opex Fusion
Opex Fusion
Why San Francisco. Why Now.

The U.S. operating landscape is being rewritten

  • AI is compressing enterprise execution cycles.
  • Manufacturing competitiveness is being redefined by reshoring, automation, and semiconductor strategy.
  • Shared services, finance, and enterprise support systems are undergoing large-scale modernization.
  • Supply chain resilience and procurement intelligence are becoming strategic competitive levers.
  • Operational excellence is no longer just about optimization.

Opex Fusion San Francisco 2026 convenes operators, manufacturers, enterprise transformation leaders, and industrial strategists around one core question:

How do you redesign operating systems for the next industrial era - without destabilizing execution?

Why San Francisco. Why Now.

Cross-Industry Enterprise Execution at Future Scale

Opex Fusion San Francisco is where operational excellence expands. It unites leaders across:

  • Manufacturing & Industrial Operation
  • Shared Services & Enterprise Transformation
  • Smart Manufacturing & Industrial AI
  • Supply Chain, Procurement & Strategic Resilience
  • Technology, Digital Infrastructure & Automation
  • Strategic Industrial Systems
WHAT MAKES SAN FRANCISCO DIFFERENT

Built for
execution
under
disruption

You will not find:

  • Abstract transformation panels
  • Generic innovation theater
  • Startup noise detached from enterprise deployment
  • Vendor-led hype

You will find:

  • Peer-level execution leadership
  • Strategic supply ecosystem discussions
  • AI + industrial modernization
  • Cross-functional scaling frameworks
  • Enterprise transformation systems
  • Match & Solve problem-solving
Why San Francisco. Why Now.

Three Tracks Defining the Future of Enterprise Execution

Track A – Operational Excellence

Modernizing enterprise execution systems

  • AI-enabled operations
  • Process excellence
  • Shared services transformation
  • GBS modernization
  • Intelligent automation
  • Governance at scale

Track B – Smart Manufacturing

Building competitive industrial systems

  • Industrial AI
  • Robotics
  • Factory modernization
  • Digital twins
  • Automation
  • Semiconductor and manufacturing competitiveness

Track C – Industrial Strategy

Scaling resilient industrial ecosystems

  • Supply chain redesign
  • Geopolitical resilience
  • Procurement modernization
  • Industrial competitiveness
  • Strategic sourcing
  • Strategic scale
Opex Fusion

Built on a system designed for execution, connection, and continuous learning.

WHO SHOULD ATTEND

Designed for leaders shaping modern enterprise systems

Industries Represented

  • Manufacturing & Industrial
  • Supply Chain & Procurement
  • Enterprise Shared Services / GBS
  • Energy & Infrastructure
  • Logistics
  • Semiconductor
  • Aerospace & Defense
  • Pharma & Life Sciences
  • Strategic Consulting
  • Financial Services Transformation
  • Consumer Goods
  • Technology & Cloud

You should attend if you are:

  • Chief Manufacturing Officer
  • COO
  • VP / SVP Operations
  • Operational Excellence Leader
  • Smart Manufacturing Leader
  • GBS / Shared Services Executive
  • Chief Supply Chain Officer
  • Procurement Transformation Leader
  • Enterprise Transformation Executive
  • Industrial Strategy Leader

If you are responsible for turning strategy into resilient, scalable operating
systems under accelerating disruption

Opex Fusion San Francisco is built for you.

Speaker Positioning

Leaders shaping future-scale enterprise execution

You should attend if you are:

  • Industrial operators
  • Enterprise modernization executives
  • Smart manufacturing pioneers
  • GBS transformation leaders
  • Supply chain strategists
  • AI-enabled execution architects
  • Strategic industrial systems thinkers
  • Vasileia Formozi

    Change Enablement & Digital Transformation Director

    Pfizer

    A change Enablement & Digital Transformation Director, with over 25 years of experience across industries, functions, and business…

  • Krisson Nandha

    Head of Operational Excellence

    Virgin

    A people-centric transformation leader with extensive experience delivering large-scale operational and organisational transformation programmes across complex global environments.…

  • Stefania Copetta

    Director – Digital Engineering Excellence

    Stellantis

    An Enterprise Transformation Leader with 15+ years of experience driving large-scale digital and organizational transformation across complex global…

  • Dr. Gunter Beitinger

    Dr. Gunter Beitinger

    Senior Vice President Manufacturing

    Siemens

    Leads Siemens’ global network of Digital Lighthouse plants, driving advanced manufacturing excellence at scale. With a background in…

  • Gerard Poolman

    Gerard Poolman

    Former Head of Operational Excellence

    Shell

    A recognized global OpEx leader, known for scaling operational excellence across industries and coaching executive teams. A seasoned…

  • David Bovis

    David Bovis

    Founder, Duxinaroe

    Conference Chair – Opex Fusion

    Explores why transformation fails—linking human behaviour, neuroscience, and operational execution. He is the founder of Duxinaroe and the…

Interested in contributing? View speaker criteria

Agenda Preview
  • Day 0
    Arrival, Workshops, Executive Networking
  • Day 1
    Strategy → Execution → Match & Solve → Fusion Night
  • Day 2
    Advanced Execution → Risk → Sustainability
SPONSORS & PARTNERS

Where industrial operators meet enterprise modernization and strategic scale

Sponsor Categories

  • Manufacturing Systems
  • Industrial AI
  • Enterprise SaaS
  • Process Mining
  • Shared Services Technology
  • Procurement Technology
  • Supply Chain Platforms
  • Automation
  • Cloud Infrastructure
  • Strategic Advisory

Explore Sponsorship Opportunities

Execution leadership is entering a new era

The enterprises that outperform in 2026 and beyond will not be those with the best isolated systems. They will be the ones that can modernize operations, manufacturing, enterprise services, and strategic supply ecosystems— Without breaking execution.

San Francisco, California | December 8–10, 2026
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