Countdown to Future-Ready Execution
May 18 – 20, 2027

Execution at Scale in the Age of AI and Industrial Realignment

May 18 –20, 2027
San Francisco, California

A cross-industry enterprise forum for leaders navigating AI acceleration, manufacturing reinvention, enterprise modernization, supply chain redesign, and strategic execution pressure.

Hero Foreground
Hero Background
Why San Francisco. Why Now.

The U.S. operating landscape is being rewritten

  • AI is compressing enterprise execution cycles.
  • Manufacturing competitiveness is being redefined by reshoring, automation, and semiconductor strategy.
  • Shared services, finance, and enterprise support systems are undergoing large-scale modernization.
  • Supply chain resilience and procurement intelligence are becoming strategic competitive levers.
  • Operational excellence is no longer just about optimization.

Opex Fusion San Francisco 2026 convenes operators, manufacturers, enterprise transformation leaders, and industrial strategists around one core question:

How do you redesign operating systems for the next industrial era – without  Destabilizing execution?

What this Event is

Cross-Industry Enterprise Execution at Future Scale

Opex Fusion San Francisco is where operational excellence expands. It unites leaders across:

  • Manufacturing & Industrial Operation
  • Shared Services & Enterprise Transformation
  • Smart Manufacturing & Industrial AI
  • Supply Chain, Procurement & Strategic Resilience
  • Technology, Digital Infrastructure & Automation
  • Strategic Industrial Systems
What makes San Francisco Different

Built for
execution
under
disruption

You will not find:

  • Abstract transformation panels
  • Generic innovation theater
  • Startup noise detached from enterprise deployment
  • Vendor-led hype

You will find:

  • Peer-level execution leadership
  • Strategic supply ecosystem discussions
  • AI + industrial modernization
  • Cross-functional scaling frameworks
  • Enterprise transformation systems
  • Match & Solve problem-solving
Core tracks

Three Tracks Defining the Future of Enterprise Execution

Track A – Operational Excellence

Transforming corporate culture and leadership delivery systems

  • Process excellence
  • Continuous improvement
  • Frontline ownership
  • Change management
  • Governance at scale
  • Operational standardisation

Track B – Enterprise Modernization 
& GBS Scale

Building autonomous, integrated backend workflows

  • Global Business Services (GBS)
  • Shared services transformation
  • Intelligent automation
  • Agentic AI execution
  • Master data integrity
  • Process mining & workflow design

Track C – Smart Manufacturing

Architecting competitive and intelligent factory floor systems

  • Industrial AI
  • Brownfield factory modernization
  • OT & IT data integration
  • Robotics & automation
  • Digital twins
  • Predictive asset analytics

Track D – Industrial Strategy
& Supply Chain

Scaling resilient, anti-fragile global networks

  • Supply chain redesign
  • Procurement modernization
  • Strategic sourcing
  • Nearshoring execution
  • Geopolitical resilience
  • Network risk management

Built on a system designed for execution, connection, and continuous learning.

Who should Attend

Designed for leaders shaping modern enterprise systems

Industries Represented

  • Manufacturing & Industrial
  • Supply Chain & Procurement
  • Enterprise Shared Services / GBS
  • Energy & Infrastructure
  • Logistics
  • Semiconductor
  • Aerospace & Defense
  • Pharma & Life Sciences
  • Strategic Consulting
  • Financial Services Transformation
  • Consumer Goods
  • Technology & Cloud

You should attend if you are:

  • Chief Manufacturing Officer
  • COO
  • VP / SVP Operations
  • Operational Excellence Leader
  • Smart Manufacturing Leader
  • GBS / Shared Services Executive
  • Chief Supply Chain Officer
  • Procurement Transformation Leader
  • Enterprise Transformation Executive
  • Industrial Strategy Leader

If you are responsible for turning strategy into resilient, scalable operating
systems under accelerating disruption

Opex Fusion San Francisco is built for you.

Speaker Positioning

Leaders shaping future-scale enterprise execution

Expect:

  • Industrial operators
  • Enterprise modernization executives
  • Smart manufacturing pioneers
  • GBS transformation leaders
  • Supply chain strategists
  • AI-enabled execution architects
  • Strategic industrial systems thinkers
Agenda Preview
  • Day 0
    Arrival | Workshops | Executive Networking
  • Day 1
    Operational Systems + Smart Manufacturing + Match & Solve + Fusion Night
  • Day 2
    Enterprise Modernization + Industrial Strategy + Scale
Sponsors & Partners

Where industrial operators meet enterprise modernization and strategic scale

Sponsor Categories

  • Manufacturing Systems
  • Industrial AI
  • Enterprise SaaS
  • Process Mining
  • Shared Services Technology
  • Procurement Technology
  • Supply Chain Platforms
  • Automation
  • Cloud Infrastructure
  • Strategic Advisory

Execution leadership is entering a new era

The enterprises that outperform in 2026 and beyond will not be those with the best isolated systems. They will be the ones that can modernize operations, manufacturing, enterprise services, and strategic supply ecosystems— Without breaking execution.

San Francisco, California | May 18 – 20, 2027
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